Designing mRNA- and Peptide-Based Vaccine Construct against Emerging Multidrug-Resistant Citrobacter freundii: A Computational-Based Subtractive Proteomics Approach
Background and Objectives: Citrobacter freundii (C.freundii) is an emerging and opportunistic Gram-negative bacteria of the human gastrointestinal tract associated with nosocomial and severe respiratory tract infections.It has also been associated with pneumonia, bloodstream, and urinary tract infections.Intrinsic and adaptive virulence characteris